Radionuclides occur naturally in groundwater and are referred to by chemists as radioactive isotopes. Radium and Uranium are both known carcinogens and along with Gross Alpha are regulated by the USEPA Safe Drinking Water Act.

Treatment technologies offered by Layne for the removal of these contaminants include: HMO with LayneOx, Low Waste Ion Exchange using Dowex RSC, Adsorptive Filtration using LayneUSR and Membrane Filtration.